Swollen Lymph Nodes and the COVID-19 Vaccine: What to Know

A vaccine reaction of enlarged lymph nodes is normal simply tin can await suspicious on mammograms and other cancer screenings. An expert explains how to avoid unnecessary worry.

If you have received a COVID-19 vaccine, you may accept experienced a reaction such as a sore arm, a headache or fatigue — normal signs that the body is mounting an immune response. But ane immune reaction tin terminate up causing unnecessary defoliation and worry. Later on the COVID-19 vaccine rollout, radiologists began to note swollen lymph nodes in the armpit, or axilla, on the mammograms of some recently vaccinated women. Enlarged nodes also accept been evident on breast CT scans to discover lung cancer and on other imaging tests.

Ordinarily, this finding can lead to the need for boosted tests or fifty-fifty biopsies to make sure it'south not a sign of cancer. Swollen armpit nodes could mean that the body is reacting to cancer in the breast or that there are cancer cells from the breast that accept spread to the lymph nodes, says Dr. Elise Desperito, chief of the Division of Breast Imaging at NewYork-Presbyterian/Columbia University Irving Medical Middle.

Dr. Elise Desperito

Even so, "Enlarged lymph nodes after the COVID vaccine are a normal response of the body," says Dr. Desperito, who is also an assistant professor of radiology at Columbia University Vagelos College of Physicians and Surgeons. "They will enlarge temporarily and return to their normal size subsequently several weeks."

Lymph nodes, pocket-size beanlike structures throughout the trunk, are an essential part of the immune system. "They contain lymphocytes, or white blood cells, which help fight infection and disease," says Dr. Desperito.

The nodes tend to nifty when they are reacting to a bacterial or viral infection. Considering COVID-nineteen vaccines prompt an immune response, they can crusade a similar reaction. The swollen glands typically appear on the side of the body where the vaccine was administered, such equally the left armpit nodes in patients who accept gotten the shot in their left arm.

It's not uncommon for vaccines to cause swollen lymph nodes afterwards vaccinations. This has occurred afterwards other immunizations, such as the H1N1 influenza vaccine. "Simply with COVID, it'southward happening on such a large scale that more people take experienced the reaction and a public conversation is needed," says Dr. Desperito.

How can you lot make sure your cancer screenings don't lead to an unnecessary cancer scare or tests? "Talking to your healthcare provider is the first, most important stride," says Dr. Desperito. She suggests the following measures:

1. Schedule Appointments Wisely

Right at present, many people are trying to schedule both their COVID-19 vaccine and cancer screenings, particularly those wanting to catch upwards on routine tests they put off due to the pandemic. "We don't desire vaccination to be delayed, and we don't want people's cancer screenings to be delayed," says Dr. Desperito.

If you lot accept the choice in scheduling appointments, schedule your imaging tests before y'all receive a COVID-19 vaccine, she advises. Then you tin can avoid having swollen lymph nodes muddy your examination results.

"Enlarged lymph nodes are visible as early on as 1 twenty-four hours after vaccination, and they can remain enlarged for a month or more," says Dr. Desperito. (Keep in mind that while you may terminate feeling a swollen lymph node, which can feel like a lump in your armpit, it may nevertheless be visible on a browse.) Call your doctor if you however feel a swollen lymph node after six weeks following your vaccine.

2. Alert Providers to Your Recent Vaccination

If you lot exercise go your COVID-xix shot before you get a cancer screening, make your providers aware of your vaccine status and then they tin manage your care accordingly.

When you take your cancer screening exam, tell the radiologist or technician when you had the first vaccine shot (and the 2d, if you received one) and in which arm. These factors should be in the report that your dr. receives.

If your test shows swollen lymph nodes, your doctor may decide to order another imaging test a few weeks later and/or lookout man yous closely before ordering a more invasive examination. For case, if a adult female had her vaccine in her left arm and enlarged lymph nodes are identified in the left axilla on her mammogram or ultrasound, a clinical exam by the patient'due south healthcare provider in 4 to six weeks, if needed, is the recommended follow-up.

But "if swelling persists, your doctor may say, 'I want you to go go an ultrasound and get information technology checked out,'" Dr. Desperito says.

3. Schedule Scans Advisedly During and Later on Cancer Treatment

If you are currently being treated for cancer or accept recovered from it, yous may be getting avant-garde imaging, such as CT scans and PET scans, periodically to see if information technology has spread to other organs or how yous are responding to handling, or to check for recurrences. Inquire your oncologist if information technology is possible to coordinate them with your vaccine date, Dr. Desperito says.

If you're offered the vaccine and you take tests coming up soon, you lot can request to have the shot administered in a unlike body office. For example, if your breast cancer is or was in the left breast, ask to become the vaccine in your right arm or fifty-fifty your thigh muscle, Dr. Desperito advises.

Talk to your doctor if swollen nodes appear on an imaging test later on you got the vaccine. "If you had a CT scan and it shows enlarged lymph nodes, a targeted ultrasound tin be washed of the axilla to see if they've gone back to normal," Dr. Desperito says. "You lot may non have to go a echo CT browse. There are other ways to bank check on it."

4. Prioritize Your Wellness

Scheduling your cancer screenings or follow-up imaging tests is very important. "We know that many people accept had to delay these screenings considering of the COVID pandemic," Dr. Desperito says. "Mostly, the earlier nosotros notice a cancer, the more treatable it is. Very just, finding cancer early saves lives."

Additional Resources

  • To acquire nearly radiology diagnostic tests at NewYork-Presbyterian, visit nyp.org/radiology.